Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50411022'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411022 (CHEMBL377154) Show SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(C)CCCc4ccccc34)C(F)(F)F)cc12 Show InChI InChI=1S/C24H23F3N2O4/c1-14-18-12-16(9-10-17(18)20(30)33-29-14)28-21(31)23(32,24(25,26)27)13-22(2)11-5-7-15-6-3-4-8-19(15)22/h3-4,6,8-10,12,32H,5,7,11,13H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of fluorescent-labeled Dexamethasone binding to GR				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411022 (CHEMBL377154) Show SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(C)CCCc4ccccc34)C(F)(F)F)cc12 Show InChI InChI=1S/C24H23F3N2O4/c1-14-18-12-16(9-10-17(18)20(30)33-29-14)28-21(31)23(32,24(25,26)27)13-22(2)11-5-7-15-6-3-4-8-19(15)22/h3-4,6,8-10,12,32H,5,7,11,13H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cells				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411022 (CHEMBL377154) Show SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(C)CCCc4ccccc34)C(F)(F)F)cc12 Show InChI InChI=1S/C24H23F3N2O4/c1-14-18-12-16(9-10-17(18)20(30)33-29-14)28-21(31)23(32,24(25,26)27)13-22(2)11-5-7-15-6-3-4-8-19(15)22/h3-4,6,8-10,12,32H,5,7,11,13H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cells				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411022 (CHEMBL377154) Show SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(C)CCCc4ccccc34)C(F)(F)F)cc12 Show InChI InChI=1S/C24H23F3N2O4/c1-14-18-12-16(9-10-17(18)20(30)33-29-14)28-21(31)23(32,24(25,26)27)13-22(2)11-5-7-15-6-3-4-8-19(15)22/h3-4,6,8-10,12,32H,5,7,11,13H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at GR assessed as MMTV-mediated transactivation of renilla luciferase gene in human A549 cells relative to Dexamethasone				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair