Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50411484'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411484 (CHEMBL391942) Show SMILES CCC1(CC(O)(Cc2[nH]c3ccccc3c2C#N)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C25H25F3N2O/c1-2-23(13-7-9-17-8-3-5-11-20(17)23)16-24(31,25(26,27)28)14-22-19(15-29)18-10-4-6-12-21(18)30-22/h3-6,8,10-12,30-31H,2,7,9,13-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.61	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411484 (CHEMBL391942) Show SMILES CCC1(CC(O)(Cc2[nH]c3ccccc3c2C#N)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C25H25F3N2O/c1-2-23(13-7-9-17-8-3-5-11-20(17)23)16-24(31,25(26,27)28)14-22-19(15-29)18-10-4-6-12-21(18)30-22/h3-6,8,10-12,30-31H,2,7,9,13-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.59	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptor				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411484 (CHEMBL391942) Show SMILES CCC1(CC(O)(Cc2[nH]c3ccccc3c2C#N)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C25H25F3N2O/c1-2-23(13-7-9-17-8-3-5-11-20(17)23)16-24(31,25(26,27)28)14-22-19(15-29)18-10-4-6-12-21(18)30-22/h3-6,8,10-12,30-31H,2,7,9,13-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells transfected with MMTV luciferase reporter gene assessed as inhibition of dexametha...				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411484 (CHEMBL391942) Show SMILES CCC1(CC(O)(Cc2[nH]c3ccccc3c2C#N)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C25H25F3N2O/c1-2-23(13-7-9-17-8-3-5-11-20(17)23)16-24(31,25(26,27)28)14-22-19(15-29)18-10-4-6-12-21(18)30-22/h3-6,8,10-12,30-31H,2,7,9,13-14,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by MMTV transactivation assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair