Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50416074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416074 (CHEMBL1085853) Show SMILES CCNS(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C22H17F4N3O2S/c1-2-28-32(30,31)18-8-9-19(20(12-18)22(24,25)26)14-3-10-21-15(11-14)13-27-29(21)17-6-4-16(23)5-7-17/h3-13,28H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416074 (CHEMBL1085853) Show SMILES CCNS(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C22H17F4N3O2S/c1-2-28-32(30,31)18-8-9-19(20(12-18)22(24,25)26)14-3-10-21-15(11-14)13-27-29(21)17-6-4-16(23)5-7-17/h3-13,28H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition of dexamethasone-induce...				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416074 (CHEMBL1085853) Show SMILES CCNS(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C22H17F4N3O2S/c1-2-28-32(30,31)18-8-9-19(20(12-18)22(24,25)26)14-3-10-21-15(11-14)13-27-29(21)17-6-4-16(23)5-7-17/h3-13,28H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Activity at GR in human A549 cells by NF-kappaB transrepression assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair