Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50416077'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416077 (CHEMBL1086115) Show SMILES CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C28H21F4N3O2S/c1-2-34(22-6-4-3-5-7-22)38(36,37)24-13-14-25(26(17-24)28(30,31)32)19-8-15-27-20(16-19)18-33-35(27)23-11-9-21(29)10-12-23/h3-18H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416077 (CHEMBL1086115) Show SMILES CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C28H21F4N3O2S/c1-2-34(22-6-4-3-5-7-22)38(36,37)24-13-14-25(26(17-24)28(30,31)32)19-8-15-27-20(16-19)18-33-35(27)23-11-9-21(29)10-12-23/h3-18H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Activity at GR in human A549 cells by NF-kappaB transrepression assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416077 (CHEMBL1086115) Show SMILES CCN(c1ccccc1)S(=O)(=O)c1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C28H21F4N3O2S/c1-2-34(22-6-4-3-5-7-22)38(36,37)24-13-14-25(26(17-24)28(30,31)32)19-8-15-27-20(16-19)18-33-35(27)23-11-9-21(29)10-12-23/h3-18H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity a...				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair