Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50416081'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416081 (CHEMBL1084360) Show SMILES CS(=O)(=O)Nc1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C21H15F4N3O2S/c1-31(29,30)27-16-5-8-18(19(11-16)21(23,24)25)13-2-9-20-14(10-13)12-26-28(20)17-6-3-15(22)4-7-17/h2-12,27H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416081 (CHEMBL1084360) Show SMILES CS(=O)(=O)Nc1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C21H15F4N3O2S/c1-31(29,30)27-16-5-8-18(19(11-16)21(23,24)25)13-2-9-20-14(10-13)12-26-28(20)17-6-3-15(22)4-7-17/h2-12,27H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition of dexamethasone-induce...				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416081 (CHEMBL1084360) Show SMILES CS(=O)(=O)Nc1ccc(-c2ccc3n(ncc3c2)-c2ccc(F)cc2)c(c1)C(F)(F)F Show InChI InChI=1S/C21H15F4N3O2S/c1-31(29,30)27-16-5-8-18(19(11-16)21(23,24)25)13-2-9-20-14(10-13)12-26-28(20)17-6-3-15(22)4-7-17/h2-12,27H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Activity at GR in human A549 cells by NF-kappaB transrepression assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair