BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Glutamate racemase' and Ligand = 'BDBM50215444'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate racemase (Helicobacter pylori)	BDBM50215444 (5-METHYL-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETH...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Global Structural Chemistry Curated by ChEMBL					Assay Description Inhibition of Helicobacter pylori glutamate racemase				Nature 447: 817-822 (2007) Article DOI: 10.1038/nature05689 BindingDB Entry DOI: 10.7270/Q2HX1DJ3
AstraZeneca Global Structural Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate racemase (Helicobacter pylori)	BDBM50215444 (5-METHYL-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETH...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of Helicobacter pylori MurI				Bioorg Med Chem Lett 18: 4716-22 (2008) Article DOI: 10.1016/j.bmcl.2008.06.092 BindingDB Entry DOI: 10.7270/Q2N29WSP
AstraZeneca R&D Boston Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate racemase (Streptococcus pneumoniae)	BDBM50215444 (5-METHYL-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETH...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Global Structural Chemistry Curated by ChEMBL					Assay Description Inhibition of MurI in Streptococcus pneumoniae				Nature 447: 817-822 (2007) Article DOI: 10.1038/nature05689 BindingDB Entry DOI: 10.7270/Q2HX1DJ3
AstraZeneca Global Structural Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate racemase (Helicobacter pylori)	BDBM50215444 (5-METHYL-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETH...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
AstraZeneca Global Structural Chemistry Curated by ChEMBL					Assay Description Binding affinity to Helicobacter pylori MurI by isothermal titration calorimetry				Nature 447: 817-822 (2007) Article DOI: 10.1038/nature05689 BindingDB Entry DOI: 10.7270/Q2HX1DJ3
AstraZeneca Global Structural Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate racemase (Helicobacter pylori)	BDBM50215444 (5-METHYL-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETH...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a
AstraZeneca Global Structural Chemistry Curated by ChEMBL					Assay Description Binding affinity to Helicobacter pylori MurI by protein fluorescence binding assay				Nature 447: 817-822 (2007) Article DOI: 10.1038/nature05689 BindingDB Entry DOI: 10.7270/Q2HX1DJ3
AstraZeneca Global Structural Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)