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Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM198672'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
5.70 -51.0n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
160 -42.0n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
180 -41.7n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
420 -39.4n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
650 -38.3n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.40E+3 -36.2n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198672
PNG
(BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...)
Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O
Show InChI InChI=1/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
5.00E+3 -32.8n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair