Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM198701'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198701 (US9221796, 28b) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC(C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C21H24N2O2/c1-15-2-4-16(5-3-15)12-22-11-10-20(21(22)25)23-13-18(14-23)17-6-8-19(24)9-7-17/h2-9,18,20,24H,10-14H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	-49.5	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
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