Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM198791'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198791 (US9221796, 83) Show SMILES Oc1ccc(cc1)[C@H]1CCN(C[C@@H]1F)[C@@H]1CCN(Cc2ccc(Cl)c(F)c2)C1=O |r| Show InChI InChI=1S/C22H23ClF2N2O2/c23-18-6-1-14(11-19(18)24)12-27-10-8-21(22(27)29)26-9-7-17(20(25)13-26)15-2-4-16(28)5-3-15/h1-6,11,17,20-21,28H,7-10,12-13H2/t17-,20+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	-51.4	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
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