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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM198814'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))
BDBM198814
PNG
(US9221796, 101, P-2)
Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(C1=O)c1ccc(OC(F)F)c(Cl)c1 |r|
Show InChI InChI=1/C22H21ClF4N2O3/c23-17-11-14(3-6-19(17)32-21(24)25)29-10-8-18(20(29)31)28-9-7-16(22(26,27)12-28)13-1-4-15(30)5-2-13/h1-6,11,16,18,21,30H,7-10,12H2/t16?,18-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
11 -49.2n/an/an/an/an/an/a50



Bristol-Myers Squibb Company

US Patent


Assay Description
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...


US Patent US9221796 (2015)


BindingDB Entry DOI: 10.7270/Q20V8BK1
More data for this
Ligand-Target Pair