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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50220577'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Rattus norvegicus (Rat))		BDBM50220577
PNG
(6-(2-(4-(3-fluorophenyl)-4-hydroxypiperidin-1-yl)-...)
Show SMILES CC(C(O)c1ccc2NC(=O)CCc2c1)N1CCC(O)(CC1)c1cccc(F)c1 |w:2.2,1.0|
Show InChI InChI=1S/C23H27FN2O3/c1-15(22(28)17-5-7-20-16(13-17)6-8-21(27)25-20)26-11-9-23(29,10-12-26)18-3-2-4-19(24)14-18/h2-5,7,13-15,22,28-29H,6,8-12H2,1H3,(H,25,27)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Pfizer Global Research & Development

Curated by ChEMBL


Assay Description
Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane

Bioorg Med Chem Lett 17: 5558-62 (2007)


Article DOI: 10.1016/j.bmcl.2007.08.014
BindingDB Entry DOI: 10.7270/Q2R21138
More data for this
Ligand-Target Pair