Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50220583'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50220583 (6-(2-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-...) Show SMILES CC(C(O)c1ccc2NC(=O)CCc2c1)N1CCC(O)(CC1)c1ccc(Cl)cc1 |w:2.2,1.0| Show InChI InChI=1S/C23H27ClN2O3/c1-15(22(28)17-2-8-20-16(14-17)3-9-21(27)25-20)26-12-10-23(29,11-13-26)18-4-6-19(24)7-5-18/h2,4-8,14-15,22,28-29H,3,9-13H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]racemic CP101606 from rat NR2B receptor in P2 membrane				Bioorg Med Chem Lett 17: 5558-62 (2007) Article DOI: 10.1016/j.bmcl.2007.08.014 BindingDB Entry DOI: 10.7270/Q2R21138
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