Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50301369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50301369 ((+)--5-Hydroxy-3-phenyl-5H-benzo[4,5]cyclohepta[1,...) Show SMILES OC1c2cccc(C#N)c2C=Cc2ncc(cc12)-c1ccccc1 |c:11| Show InChI InChI=1S/C21H14N2O/c22-12-15-7-4-8-18-17(15)9-10-20-19(21(18)24)11-16(13-23-20)14-5-2-1-3-6-14/h1-11,13,21,24H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonistic activity against NR2B receptor expressed in mouse Ltk cells assessed as inhibition of calcium influx by FLIPR assay				Bioorg Med Chem Lett 19: 5132-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.028 BindingDB Entry DOI: 10.7270/Q2X34XJW
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