Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Binding affinity against human GluR6 | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Displacement of [3H]kainate from rat GLUK6 receptor expressed in HEK293 cells | J Med Chem 48: 7867-81 (2005) Article DOI: 10.1021/jm050584l BindingDB Entry DOI: 10.7270/Q2V69KCT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells | J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human)) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Effective concentration against human GluR6 expressed in HEK293 cells | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair |