Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM108853'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108853 (US8604016, 433 | US9938267, Cmpd ID 433) Show SMILES CC(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-22(2)17-28(40)33-21-25-12-8-11-24(18-25)20-30(42)35-32-39-38-31(43-32)14-7-6-13-26-15-16-27(37-36-26)34-29(41)19-23-9-4-3-5-10-23/h3-5,8-12,15-16,18,22H,6-7,13-14,17,19-21H2,1-2H3,(H,33,40)(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108853 (US8604016, 433 | US9938267, Cmpd ID 433) Show SMILES CC(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-22(2)17-28(40)33-21-25-12-8-11-24(18-25)20-30(42)35-32-39-38-31(43-32)14-7-6-13-26-15-16-27(37-36-26)34-29(41)19-23-9-4-3-5-10-23/h3-5,8-12,15-16,18,22H,6-7,13-14,17,19-21H2,1-2H3,(H,33,40)(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair