Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM108878'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108878 (US8604016, 458 | US9938267, Cmpd ID 458) Show SMILES FC(F)(F)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C29H28F3N7O3S/c30-29(31,32)27(42)33-18-21-10-6-9-20(15-21)17-25(41)35-28-39-38-26(43-28)12-5-4-11-22-13-14-23(37-36-22)34-24(40)16-19-7-2-1-3-8-19/h1-3,6-10,13-15H,4-5,11-12,16-18H2,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108878 (US8604016, 458 | US9938267, Cmpd ID 458) Show SMILES FC(F)(F)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C29H28F3N7O3S/c30-29(31,32)27(42)33-18-21-10-6-9-20(15-21)17-25(41)35-28-39-38-26(43-28)12-5-4-11-22-13-14-23(37-36-22)34-24(40)16-19-7-2-1-3-8-19/h1-3,6-10,13-15H,4-5,11-12,16-18H2,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair