BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glutamine synthetase' and Ligand = 'BDBM50174521'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamine synthetase (Escherichia coli (strain K12))	BDBM50174521 ((S)-2-Amino-4-[((S)-1-amino-ethyl)-hydroxy-phosphi...) Show SMILES CC(=N)P(O)(O)CC[C@H](N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards glutamine synthetase				J Med Chem 48: 6340-9 (2005) Article DOI: 10.1021/jm050474e BindingDB Entry DOI: 10.7270/Q29C6Z6R
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine synthetase (Escherichia coli (strain K12))	BDBM50174521 ((S)-2-Amino-4-[((S)-1-amino-ethyl)-hydroxy-phosphi...) Show SMILES CC(=N)P(O)(O)CC[C@H](N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards glutamine synthetase				J Med Chem 48: 6340-9 (2005) Article DOI: 10.1021/jm050474e BindingDB Entry DOI: 10.7270/Q29C6Z6R
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine synthetase (Escherichia coli (strain K12))	BDBM50174521 ((S)-2-Amino-4-[((S)-1-amino-ethyl)-hydroxy-phosphi...) Show SMILES CC(=N)P(O)(O)CC[C@H](N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	7.4	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibitory concentration against glutamine synthetase incubated at 37 degree C for 20 minutes in pH 7.4				J Med Chem 48: 6340-9 (2005) Article DOI: 10.1021/jm050474e BindingDB Entry DOI: 10.7270/Q29C6Z6R
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine synthetase (Escherichia coli (strain K12))	BDBM50174521 ((S)-2-Amino-4-[((S)-1-amino-ethyl)-hydroxy-phosphi...) Show SMILES CC(=N)P(O)(O)CC[C@H](N)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.4	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibitory concentration against glutamine synthetase incubated at 37 degree C for 20 minutes in pH 7.4				J Med Chem 48: 6340-9 (2005) Article DOI: 10.1021/jm050474e BindingDB Entry DOI: 10.7270/Q29C6Z6R
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair