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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM124350'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM124350
PNG
(CHEMBL2071607 | US8759532, 1)
Show SMILES FC(F)(F)c1cccnc1Oc1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1
Show InChI InChI=1S/C20H12F3N5O/c21-20(22,23)15-2-1-9-25-18(15)29-14-6-4-13(5-7-14)26-19-27-16-8-3-12(11-24)10-17(16)28-19/h1-10H,(H2,26,27,28)
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n/an/a 3.08E+4n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GSK3beta by AlphaScreen assay

Bioorg Med Chem Lett 22: 5392-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.046
BindingDB Entry DOI: 10.7270/Q2CF9R6Q
More data for this
Ligand-Target Pair