Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM235822'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM235822 (US9364459, J) Show SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1cn(CCN(C)C)c2ccccc12 |t:13| Show InChI InChI=1S/C25H27N3O5/c1-27(2)10-11-28-14-17(16-8-6-7-9-18(16)28)22-21(24(29)26-25(22)30)15-12-19(31-3)23(33-5)20(13-15)32-4/h6-9,12-14H,10-11H2,1-5H3,(H,26,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Mainz; Universitätsmedizin der Johannes Gutenberg-Universität Mainz US Patent					Assay Description The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...				US Patent US9364459 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5FK2
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