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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50133066'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50133066
PNG
(17,20-dioxa-4,12,14,23,25-pentaazahexacyclo[21.6.1...)
Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCn3cc2c2cccnc32)c2ncccc12 |c:5|
Show InChI InChI=1S/C24H21N5O4/c30-23-19-17-13-28(21-15(17)3-1-5-25-21)7-9-32-11-12-33-10-8-29-14-18(20(19)24(31)27-23)16-4-2-6-26-22(16)29/h1-6,13-14H,7-12H2,(H,27,30,31)
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MMDB

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Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of Glycogen synthase kinase-3beta (GSK3-beta)


J Med Chem 46: 4021-31 (2003)


Article DOI: 10.1021/jm030115o
BindingDB Entry DOI: 10.7270/Q2G44R1D
More data for this
Ligand-Target Pair