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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50293677'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50293677
PNG
(2-(3-chlorophenylthio)-N-(5-methyl-1H-pyrazol-3-yl...)
Show SMILES Cc1cc(Nc2nc(Sc3cccc(Cl)c3)nc3ccccc23)[nH]n1
Show InChI InChI=1S/C18H14ClN5S/c1-11-9-16(24-23-11)21-17-14-7-2-3-8-15(14)20-18(22-17)25-13-6-4-5-12(19)10-13/h2-10H,1H3,(H2,20,21,22,23,24)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
33n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL


Assay Description
Inhibition of GSK3-beta


Bioorg Med Chem Lett 19: 3586-92 (2009)


Article DOI: 10.1016/j.bmcl.2009.04.136
BindingDB Entry DOI: 10.7270/Q28K7944
More data for this
Ligand-Target Pair