BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50337557'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50337557 ((S)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 mins				Bioorg Med Chem Lett 21: 1429-33 (2011) Article DOI: 10.1016/j.bmcl.2011.01.017 BindingDB Entry DOI: 10.7270/Q2KH0NNF
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50337557 ((S)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrs				Bioorg Med Chem Lett 21: 1429-33 (2011) Article DOI: 10.1016/j.bmcl.2011.01.017 BindingDB Entry DOI: 10.7270/Q2KH0NNF
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair