Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM8574'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM8574 (4-Acylamino-6-arylfuro[2,3-d]pyrimidine 19 | N-[6-...) Show SMILES O=C(Nc1ncnc2oc(cc12)-c1cccnc1)C1CC1 Show InChI InChI=1S/C15H12N4O2/c20-14(9-3-4-9)19-13-11-6-12(10-2-1-5-16-7-10)21-15(11)18-8-17-13/h1-2,5-9H,3-4H2,(H,17,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human Protein kinase C beta 2				Eur J Med Chem 164: 448-470 (2019) Article DOI: 10.1016/j.ejmech.2018.12.073 BindingDB Entry DOI: 10.7270/Q2WH2SVB
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM8574 (4-Acylamino-6-arylfuro[2,3-d]pyrimidine 19 | N-[6-...) Show SMILES O=C(Nc1ncnc2oc(cc12)-c1cccnc1)C1CC1 Show InChI InChI=1S/C15H12N4O2/c20-14(9-3-4-9)19-13-11-6-12(10-2-1-5-16-7-10)21-15(11)18-8-17-13/h1-2,5-9H,3-4H2,(H,17,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.2	22
Tsukuba Research Laboratories					Assay Description The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...				Bioorg Med Chem Lett 14: 3907-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.064 BindingDB Entry DOI: 10.7270/Q2XD0ZWC
					More data for this Ligand-Target Pair