Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50213673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213673 ((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(pyridin-4-y...) Show SMILES C[C@H](CNCCc1ccncc1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C33H38N4O/c1-23-17-24(2)19-28(18-23)33-32(25(3)21-35-15-11-26-9-13-34-14-10-26)29-22-37(16-12-30(29)36-33)31(38)20-27-7-5-4-6-8-27/h4-10,13-14,17-19,25,35-36H,11-12,15-16,20-22H2,1-3H3/t25-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHR				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213673 ((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(pyridin-4-y...) Show SMILES C[C@H](CNCCc1ccncc1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C33H38N4O/c1-23-17-24(2)19-28(18-23)33-32(25(3)21-35-15-11-26-9-13-34-14-10-26)29-22-37(16-12-30(29)36-33)31(38)20-27-7-5-4-6-8-27/h4-10,13-14,17-19,25,35-36H,11-12,15-16,20-22H2,1-3H3/t25-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of GnRHR in rat pituitary cells assessed as inhibition of GnRH-stimulated LH release				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50213673 ((S)-1-(2-(3,5-dimethylphenyl)-3-(1-(2-(pyridin-4-y...) Show SMILES C[C@H](CNCCc1ccncc1)c1c2CN(CCc2[nH]c1-c1cc(C)cc(C)c1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C33H38N4O/c1-23-17-24(2)19-28(18-23)33-32(25(3)21-35-15-11-26-9-13-34-14-10-26)29-22-37(16-12-30(29)36-33)31(38)20-27-7-5-4-6-8-27/h4-10,13-14,17-19,25,35-36H,11-12,15-16,20-22H2,1-3H3/t25-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysis				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
					More data for this Ligand-Target Pair