Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Growth hormone-releasing hormone receptor' and Ligand = 'BDBM50004974'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone-releasing hormone receptor (Rattus norvegicus)	BDBM50004974 (Ac-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys...) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O Show InChI InChI=1S/C151H248N44O43S/c1-21-78(13)118(193-124(214)82(17)169-134(224)106(67-115(207)208)180-123(213)81(16)168-133(223)102(171-84(19)200)64-86-40-44-88(201)45-41-86)147(237)187-104(63-85-33-24-23-25-34-85)140(230)195-120(83(18)199)148(238)188-105(66-113(156)205)139(229)191-110(72-198)144(234)184-103(65-87-42-46-89(202)47-43-87)138(228)177-94(39-32-57-166-151(162)163)127(217)176-92(36-27-29-54-153)132(222)192-117(77(11)12)145(235)186-98(59-73(3)4)125(215)167-69-114(206)172-95(48-50-111(154)203)129(219)182-101(62-76(9)10)137(227)190-108(70-196)142(232)170-80(15)122(212)174-93(38-31-56-165-150(160)161)126(216)175-91(35-26-28-53-152)128(218)181-100(61-75(7)8)136(226)183-99(60-74(5)6)135(225)178-96(49-51-112(155)204)130(220)185-107(68-116(209)210)141(231)194-119(79(14)22-2)146(236)179-97(52-58-239-20)131(221)189-109(71-197)143(233)173-90(121(157)211)37-30-55-164-149(158)159/h23-25,33-34,40-47,73-83,90-110,117-120,196-199,201-202H,21-22,26-32,35-39,48-72,152-153H2,1-20H3,(H2,154,203)(H2,155,204)(H2,156,205)(H2,157,211)(H,167,215)(H,168,223)(H,169,224)(H,170,232)(H,171,200)(H,172,206)(H,173,233)(H,174,212)(H,175,216)(H,176,217)(H,177,228)(H,178,225)(H,179,236)(H,180,213)(H,181,218)(H,182,219)(H,183,226)(H,184,234)(H,185,220)(H,186,235)(H,187,237)(H,188,238)(H,189,221)(H,190,227)(H,191,229)(H,192,222)(H,193,214)(H,194,231)(H,195,230)(H,207,208)(H,209,210)(H4,158,159,164)(H4,160,161,165)(H4,162,163,166)/t78-,79-,80-,81-,82-,83+,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,117-,118-,119-,120-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Notre-Dame Hospital Research Curated by ChEMBL					Assay Description Compound was tested to Inhibit [125I]-Growth hormone-releasing factor in rat adenopituitary homogenates				J Med Chem 35: 1864-9 (1992) BindingDB Entry DOI: 10.7270/Q2Z0373P
					More data for this Ligand-Target Pair