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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HIV-1 Reverse Transcriptase' and Ligand = 'BDBM2485'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Reverse Transcriptase


(Human immunodeficiency virus type 1)
BDBM2485
PNG
(2-(cyclopentylamino)-6-[(2,6-difluorophenyl)methyl...)
Show SMILES Fc1cccc(F)c1Cc1cc(=O)[nH]c(NC2CCCC2)n1
Show InChI InChI=1S/C16H17F2N3O/c17-13-6-3-7-14(18)12(13)8-11-9-15(22)21-16(20-11)19-10-4-1-2-5-10/h3,6-7,9-10H,1-2,4-5,8H2,(H2,19,20,21,22)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 70n/an/an/an/a7.837



Universita degli Studi di Roma La Sapienza



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 47: 928-34 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.058
BindingDB Entry DOI: 10.7270/Q26W988R
More data for this
Ligand-Target Pair