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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HIV-1 Reverse Transcriptase' and Ligand = 'BDBM2864'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Reverse Transcriptase


(Human immunodeficiency virus type 1)
BDBM2864
PNG
(3-(5-bromopyridin-2-yl)-1-[3-(2-methoxyphenyl)-3-o...)
Show SMILES COc1ccccc1C(=O)CCNC(=S)Nc1ccc(Br)cn1
Show InChI InChI=1S/C16H16BrN3O2S/c1-22-14-5-3-2-4-12(14)13(21)8-9-18-16(23)20-15-7-6-11(17)10-19-15/h2-7,10H,8-9H2,1H3,(H2,18,19,20,23)
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/a7.837



Medivir AB



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


Bioorg Med Chem Lett 10: 265-8 (2000)


Article DOI: 10.1021/jm050896o
BindingDB Entry DOI: 10.7270/Q2DF6PDR
More data for this
Ligand-Target Pair