Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HIV-1 protease' and Ligand = 'BDBM275783'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 protease (Human immunodeficiency virus)	BDBM275783 (US10071110, Compound HDP-ADV) Show SMILES CCCCCCCCCCCCCCCCOCCCOP(O)(=O)COCn1cnc2c(N)ncnc12 Show InChI InChI=1S/C26H48N5O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-34-18-16-19-36-37(32,33)23-35-22-31-21-30-24-25(27)28-20-29-26(24)31/h20-21H,2-19,22-23H2,1H3,(H,32,33)(H2,27,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Preliminary experiments in the inhibition of HIV-1 replication by invention compounds were performed as follows. Drug assays were carried out as prev...				US Patent US10071110 (2018) BindingDB Entry DOI: 10.7270/Q2NS0WX9
					More data for this Ligand-Target Pair