Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM152275'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM152275 (US8993556, 5-[2-(4-Chlorophenoxy)-4,6-dihydroxyphe...) Show SMILES CCNC(=O)c1cc(on1)-c1c(O)cc(O)cc1Oc1ccc(Cl)cc1 Show InChI InChI=1S/C18H15ClN2O5/c1-2-20-18(24)13-9-16(26-21-13)17-14(23)7-11(22)8-15(17)25-12-5-3-10(19)4-6-12/h3-9,22-23H,2H2,1H3,(H,20,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	9.20	n/a	n/a	n/a	7.6	n/a
Nerviano Medical Sciences S.R.L. US Patent					Assay Description The evaluation of the binding affinity (KD) of the compounds of formula (I) to the HSP90 protein was done using Biacore T100.His-HSP90 N-term domain ...				US Patent US8993556 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BSQ
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