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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatic Lipase (HL)' and Ligand = 'BDBM151284'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151284
PNG
(US8987314, B80)
Show SMILES Cc1nnc(CNC(=O)C(c2nc3cc(C)c(cc3s2)-c2ccc(F)nc2)S(C)(=O)=O)o1
Show InChI InChI=1/C20H18FN5O4S2/c1-10-6-14-15(7-13(10)12-4-5-16(21)22-8-12)31-20(24-14)18(32(3,28)29)19(27)23-9-17-26-25-11(2)30-17/h4-8,18H,9H2,1-3H3,(H,23,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair