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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatic Lipase (HL)' and Ligand = 'BDBM151441'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM151441
PNG
(US8987314, B252)
Show SMILES CC(C)c1cc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)on1
Show InChI InChI=1/C23H23N3O4S2/c1-14(2)19-12-17(30-26-19)13-24-22(27)21(32(3,28)29)23-25-18-10-9-16(11-20(18)31-23)15-7-5-4-6-8-15/h4-12,14,21H,13H2,1-3H3,(H,24,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.40n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair