new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor activator' and Ligand = 'BDBM50032932'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50032932
PNG
(CHEMBL3356593)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nccs1 |r|
Show InChI InChI=1/C32H49N9O5S/c1-20(2)18-25(29(45)39-23(13-9-15-37-32(34)35)27(43)31-36-16-17-47-31)40-30(46)26(19-22-10-5-4-6-11-22)41-28(44)24(38-21(3)42)12-7-8-14-33/h4-6,10-11,16-17,20,23-26H,7-9,12-15,18-19,33H2,1-3H3,(H,38,42)(H,39,45)(H,40,46)(H,41,44)(H4,34,35,37)/t23-,24-,25-,26-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
80n/an/an/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assay


ACS Med Chem Lett 5: 1219-24 (2014)


Article DOI: 10.1021/ml500254r
BindingDB Entry DOI: 10.7270/Q2VM4DV8
More data for this
Ligand-Target Pair