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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor activator' and Ligand = 'BDBM50032934'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50032934
PNG
(CHEMBL3356591)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nccs1 |r|
Show InChI InChI=1/C33H46N10O6S/c1-18(2)15-25(30(48)41-23(9-6-12-38-33(35)36)28(46)32-37-13-14-50-32)43-29(47)24(10-11-27(34)45)42-31(49)26(40-19(3)44)16-20-17-39-22-8-5-4-7-21(20)22/h4-5,7-8,13-14,17-18,23-26,39H,6,9-12,15-16H2,1-3H3,(H2,34,45)(H,40,44)(H,41,48)(H,42,49)(H,43,47)(H4,35,36,38)/t23-,24-,25-,26-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
65n/an/an/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assay


ACS Med Chem Lett 5: 1219-24 (2014)


Article DOI: 10.1021/ml500254r
BindingDB Entry DOI: 10.7270/Q2VM4DV8
More data for this
Ligand-Target Pair