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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor activator' and Ligand = 'BDBM50069109'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor activator


(Homo sapiens (Human))		BDBM50069109
PNG
(CHEMBL3402438)
Show SMILES NC(=N)c1cccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCC[C@H](C2)NC(=O)OCc2ccccc2)c1 |r|
Show InChI InChI=1S/C33H35N5O5S/c34-31(35)27-13-6-10-24(18-27)19-30(37-44(41,42)29-16-15-25-11-4-5-12-26(25)20-29)32(39)38-17-7-14-28(21-38)36-33(40)43-22-23-8-2-1-3-9-23/h1-6,8-13,15-16,18,20,28,30,37H,7,14,17,19,21-22H2,(H3,34,35)(H,36,40)/t28-,30+/m1/s1
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PC cid
PC sid
UniChem

Similars
Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells using Boc-QLR-AMC as substrate incu...

Bioorg Med Chem 23: 2328-43 (2015)


Article DOI: 10.1016/j.bmc.2015.03.072
BindingDB Entry DOI: 10.7270/Q23F4RB4
More data for this
Ligand-Target Pair