Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM124886'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124886 (US8759341, 2) Show SMILES Cc1[nH]nc2ccc(cc12)C1C([N+]#[C-])C(C)=NC2=C1C(=O)OC2 |c:17,19| Show InChI InChI=1S/C17H14N4O2/c1-8-11-6-10(4-5-12(11)21-20-8)14-15-13(7-23-17(15)22)19-9(2)16(14)18-3/h4-6,14,16H,7H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	22
Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 mL of a 100-fold concentrated solution of the test compound in DMSO is pipetted into a black low-volume 384-well microtiter plate (...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM124886 (US8759341, 2) Show SMILES Cc1[nH]nc2ccc(cc12)C1C([N+]#[C-])C(C)=NC2=C1C(=O)OC2 |c:17,19| Show InChI InChI=1S/C17H14N4O2/c1-8-11-6-10(4-5-12(11)21-20-8)14-15-13(7-23-17(15)22)19-9(2)16(14)18-3/h4-6,14,16H,7H2,1-2H3,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	25
Bayer Intellectual Property GmbH US Patent					Assay Description Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...				US Patent US8759341 (2014) BindingDB Entry DOI: 10.7270/Q2HQ3XMW
					More data for this Ligand-Target Pair