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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM355865'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM355865
PNG
(N-(4-((5-(3-aminomethylphenyl)pyrrolo[1,2-b]pyrida...)
Show SMILES NCc1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12
Show InChI InChI=1S/C31H25F2N5O3/c32-21-4-6-22(7-5-21)36-29(39)31(12-13-31)30(40)37-23-8-9-26(25(33)17-23)41-27-10-14-35-38-15-11-24(28(27)38)20-3-1-2-19(16-20)18-34/h1-11,14-17H,12-13,18,34H2,(H,36,39)(H,37,40)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<40n/an/an/an/an/an/a



The Asan Foundation

US Patent


Assay Description
The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...


US Patent US9815840 (2017)


BindingDB Entry DOI: 10.7270/Q2862JQZ
More data for this
Ligand-Target Pair