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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM355870'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM355870
PNG
(N-(4-((5-(3-amino-4-methyl)-5-fluorophenyl)pyrrolo...)
Show SMILES Cc1ccc(cc1N)-c1ccn2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)c12
Show InChI InChI=1S/C31H25F2N5O3/c1-18-2-3-19(16-25(18)34)23-11-15-38-28(23)27(10-14-35-38)41-26-9-8-22(17-24(26)33)37-30(40)31(12-13-31)29(39)36-21-6-4-20(32)5-7-21/h2-11,14-17H,12-13,34H2,1H3,(H,36,39)(H,37,40)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a<40n/an/an/an/an/an/a



The Asan Foundation

US Patent


Assay Description
The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...


US Patent US9815840 (2017)


BindingDB Entry DOI: 10.7270/Q2862JQZ
More data for this
Ligand-Target Pair