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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50010390'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50010390
PNG
(CHEMBL3263966)
Show SMILES COc1cc2c(Oc3ccc(NS(=O)(=O)c4ccc(cc4)-c4cnn(C)c4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C34H37FN6O5S/c1-39-14-16-41(17-15-39)13-4-18-45-34-21-30-28(20-33(34)44-3)31(11-12-36-30)46-32-10-7-26(19-29(32)35)38-47(42,43)27-8-5-24(6-9-27)25-22-37-40(2)23-25/h5-12,19-23,38H,4,13-18H2,1-3H3
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PC cid
PC sid
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Article
PubMed
n/an/a 1.23E+3n/an/an/an/an/an/a



Vichem Chemie Research Ltd.

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly-AEKY peptide as substrate after 60 mins by ADPGlo assay


ACS Med Chem Lett 5: 298-303 (2014)


Article DOI: 10.1021/ml4003309
BindingDB Entry DOI: 10.7270/Q2HD7X6X
More data for this
Ligand-Target Pair