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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50021577'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50021577
PNG
(CHEMBL3290903)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5OC(F)(F)F)c(=O)cc4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C37H36F4N6O6/c1-23-19-34(48)47(28-7-4-5-8-31(28)53-37(39,40)41)44-35(23)36(49)43-24-9-10-30(26(38)20-24)52-29-11-12-42-27-22-33(32(50-3)21-25(27)29)51-18-6-13-46-16-14-45(2)15-17-46/h4-5,7-12,19-22H,6,13-18H2,1-3H3,(H,43,49)
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PC cid
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Similars
Article
PubMed
n/an/a 8.30n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate by homogeneous time-resolved fluorescence assay

Eur J Med Chem 83: 581-93 (2014)


Article DOI: 10.1016/j.ejmech.2014.06.068
BindingDB Entry DOI: 10.7270/Q2R78GTF
More data for this
Ligand-Target Pair