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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50023335'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50023335
PNG
(CHEMBL3334540)
Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1
Show InChI InChI=1S/C17H12F3N9/c18-17(19,20)10-28-9-12(5-23-28)13-6-22-15-16(24-13)29(26-25-15)8-11-1-2-14-21-3-4-27(14)7-11/h1-7,9H,8,10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Hutchison MediPharma Limited

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay


J Med Chem 57: 7577-89 (2014)


Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50023335
PNG
(CHEMBL3334540)
Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1
Show InChI InChI=1S/C17H12F3N9/c18-17(19,20)10-28-9-12(5-23-28)13-6-22-15-16(24-13)29(26-25-15)8-11-1-2-14-21-3-4-27(14)7-11/h1-7,9H,8,10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Hutchison MediPharma Limited

Curated by ChEMBL


Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA


J Med Chem 57: 7577-89 (2014)


Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR
More data for this
Ligand-Target Pair