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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50035427'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50035427
PNG
(CHEMBL3343400)
Show SMILES COc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CCN(C)CC5)c(OC)cc34)c(F)c2)c1C(F)(F)F
Show InChI InChI=1S/C35H35F4N7O5/c1-44-14-16-45(17-15-44)13-4-18-50-31-21-27-25(20-30(31)49-3)28(11-12-40-27)51-29-10-5-22(19-26(29)36)41-34(47)32-33(35(37,38)39)46(43-42-32)23-6-8-24(48-2)9-7-23/h5-12,19-21H,4,13-18H2,1-3H3,(H,41,47)
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Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay

Bioorg Med Chem 22: 6438-52 (2014)


Article DOI: 10.1016/j.bmc.2014.09.037
BindingDB Entry DOI: 10.7270/Q2BG2QM2
More data for this
Ligand-Target Pair