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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50065500'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50065500
PNG
(CHEMBL3402750)
Show SMILES Cc1cnc(s1)-c1cccc(Cn2nc(ccc2=O)-c2cc(F)cc(F)c2)c1
Show InChI InChI=1S/C21H15F2N3OS/c1-13-11-24-21(28-13)15-4-2-3-14(7-15)12-26-20(27)6-5-19(25-26)16-8-17(22)10-18(23)9-16/h2-11H,12H2,1H3
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MMDB

KEGG

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PC cid
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Similars
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Merck Serono Research& Development

Curated by ChEMBL


Assay Description
Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assay

Bioorg Med Chem Lett 25: 1597-602 (2015)


Article DOI: 10.1016/j.bmcl.2015.02.002
BindingDB Entry DOI: 10.7270/Q2HX1FBT
More data for this
Ligand-Target Pair