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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50065505'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50065505
PNG
(CHEMBL3402745)
Show SMILES CCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-c2cc(F)cc(F)c2)c1
Show InChI InChI=1S/C20H17F2N3O3/c1-2-28-20(27)23-17-5-3-4-13(8-17)12-25-19(26)7-6-18(24-25)14-9-15(21)11-16(22)10-14/h3-11H,2,12H2,1H3,(H,23,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Serono Research& Development

Curated by ChEMBL


Assay Description
Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assay


Bioorg Med Chem Lett 25: 1597-602 (2015)


Article DOI: 10.1016/j.bmcl.2015.02.002
BindingDB Entry DOI: 10.7270/Q2HX1FBT
More data for this
Ligand-Target Pair