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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50079558'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50079558
PNG
(CHEMBL3417482)
Show SMILES CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1
Show InChI InChI=1S/C28H31FN6O3/c1-32-13-15-33(16-14-32)11-3-17-38-28(37)30-24-5-2-4-21(18-24)20-35-27(36)9-8-26(31-35)34-12-10-22-6-7-23(29)19-25(22)34/h2,4-10,12,18-19H,3,11,13-17,20H2,1H3,(H,30,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method


Eur J Med Chem 95: 302-12 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.041
BindingDB Entry DOI: 10.7270/Q2GQ70G4
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50079558
PNG
(CHEMBL3417482)
Show SMILES CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(ccc3=O)-n3ccc4ccc(F)cc34)c2)CC1
Show InChI InChI=1S/C28H31FN6O3/c1-32-13-15-33(16-14-32)11-3-17-38-28(37)30-24-5-2-4-21(18-24)20-35-27(36)9-8-26(31-35)34-12-10-22-6-7-23(29)19-25(22)34/h2,4-10,12,18-19H,3,11,13-17,20H2,1H3,(H,30,37)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Shanghai Institute of Materia Medica

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-MET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA


Eur J Med Chem 115: 191-200 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.027
BindingDB Entry DOI: 10.7270/Q28K7BZ9
More data for this
Ligand-Target Pair