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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50143252'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50143252
PNG
(CHEMBL3758905)
Show SMILES Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3ncc(cn3)-c3cccnc3)c2)n1
Show InChI InChI=1S/C24H20N8O/c1-31-16-20(14-28-31)22-7-8-23(33)32(30-22)15-17-4-2-6-21(10-17)29-24-26-12-19(13-27-24)18-5-3-9-25-11-18/h2-14,16H,15H2,1H3,(H,26,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA


Eur J Med Chem 108: 322-33 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.042
BindingDB Entry DOI: 10.7270/Q2DJ5HG7
More data for this
Ligand-Target Pair