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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50152681'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50152681
PNG
(CHEMBL3781197)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCCCC1
Show InChI InChI=1S/C40H35ClF2N4O5/c1-50-35-23-29-31(24-36(35)51-21-7-20-46-18-5-2-6-19-46)44-17-16-33(29)52-34-15-12-26(22-30(34)43)45-39(48)37-38(41)28-8-3-4-9-32(28)47(40(37)49)27-13-10-25(42)11-14-27/h3-4,8-17,22-24H,2,5-7,18-21H2,1H3,(H,45,48)
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Similars
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Jiangxi Science and Technology Normal University

Curated by ChEMBL


Assay Description
Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem Lett 26: 1794-8 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.037
BindingDB Entry DOI: 10.7270/Q2TT4ST4
More data for this
Ligand-Target Pair