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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50205142'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50205142
PNG
(CHEMBL3954957)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccc(OC(F)F)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C36H37F3N6O6/c1-22-12-16-44(17-13-22)15-4-18-49-32-21-28-26(20-31(32)48-3)29(11-14-40-28)51-30-10-5-23(19-27(30)37)41-34(46)33-42-45(36(47)43(33)2)24-6-8-25(9-7-24)50-35(38)39/h5-11,14,19-22,35H,4,12-13,15-18H2,1-3H3,(H,41,46)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 8.70n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using poly(Glu, Tyr)4:1 as substrate after 30 mins by HTRF assay

Eur J Med Chem 123: 431-446 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.059
BindingDB Entry DOI: 10.7270/Q2KK9DR0
More data for this
Ligand-Target Pair