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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50245264'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50245264
PNG
(CHEMBL510112 | N-[({5-[(6,7-Dimethoxyquinolin-4-yl...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cn3)c2cc1OC
Show InChI InChI=1S/C25H22N4O4S/c1-31-21-13-18-19(14-22(21)32-2)26-11-10-20(18)33-24-9-8-17(15-27-24)28-25(34)29-23(30)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H2,28,29,30,34)
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 3n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human activated c-Met by PK/LDH coupled kinetic assay

Eur J Med Chem 43: 1321-9 (2008)


Article DOI: 10.1016/j.ejmech.2007.08.011
BindingDB Entry DOI: 10.7270/Q2HX1CGS
More data for this
Ligand-Target Pair