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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50245431'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50245431
PNG
(CHEMBL472552 | N-[({5-[(6,7-Dimethoxyquinolin-4-yl...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4)nc3)c2cc1OC
Show InChI InChI=1S/C24H20N4O5/c1-31-20-12-17-18(13-21(20)32-2)25-11-10-19(17)33-16-8-9-22(26-14-16)27-24(30)28-23(29)15-6-4-3-5-7-15/h3-14H,1-2H3,(H2,26,27,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
50n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human activated c-Met by PK/LDH coupled kinetic assay


Eur J Med Chem 43: 1321-9 (2008)


Article DOI: 10.1016/j.ejmech.2007.08.011
BindingDB Entry DOI: 10.7270/Q2HX1CGS
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50245431
PNG
(CHEMBL472552 | N-[({5-[(6,7-Dimethoxyquinolin-4-yl...)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4)nc3)c2cc1OC
Show InChI InChI=1S/C24H20N4O5/c1-31-20-12-17-18(13-21(20)32-2)25-11-10-19(17)33-16-8-9-22(26-14-16)27-24(30)28-23(29)15-6-4-3-5-7-15/h3-14H,1-2H3,(H2,26,27,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 480n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair