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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50251300'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50251300
PNG
(CHEMBL4066684)
Show SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)-c1ccc(F)cc1
Show InChI InChI=1S/C25H17F2N5O3/c1-14-12-22(33)32(17-5-2-15(26)3-6-17)31-23(14)25(34)30-16-4-7-21(19(27)13-16)35-20-9-11-29-24-18(20)8-10-28-24/h2-13H,1H3,(H,28,29)(H,30,34)
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MMDB

KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



School of Pharmacy, Jiangxi Science and Technology Normal University, Nanchang 330013, PR China. Electronic address: tangqidongcn@126.com.

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Eur J Med Chem 133: 97-106 (2017)


Article DOI: 10.1016/j.ejmech.2017.03.045
BindingDB Entry DOI: 10.7270/Q2K35X3B
More data for this
Ligand-Target Pair